Skip to main content Skip to main navigation menu Skip to site footer

Gambaran sindrom metabolik pada pasien gangguan jiwa yang dirawat di rumah sakit jiwa provinsi Bali


Introduction: Metabolic syndrome (MS) is a constellation of various disorders that can increase the risk of heart disease. MS is known to increase morbidity and mortality rates in psychiatric patients. However, MS in the population of mental disorders, especially in Bali, is still not well known.

Methods: A cross-sectional analytic descriptive study was conducted in psychiatric patients treated at Bali Provincial Mental Hospital from January 2018 to February 2018. Inclusion criteria included inpatients who diagnosed with mental disorders based on DSM-IV criteria and those who had MS based on the National Cholesterol Education Program Adult Treatment Panel (NCE ATP III) criteria.

Results: A total of 245 samples were included in this study with the prevalence of MS was 48.6%. According on sex, female had higher proportion among MS patients than male (42.8% vs 60.7%). In addition, the age group > 65 years had the highest frequency (75%) suffered from MS followed by age group of 45-65 years (54,9%). Based on the class of antipsychotic administered, MS patients with typical antipsychotic drug classes had the highest frequency, followed by the atypical group and combination of atypical and typical (49.4%, 49.3%, and 46.2%, respectively). Among MS patients, most of them had obesity (87.3%), followed by dyslipidemia, hypertension and impaired fasting glucose (76.4%, 65.5%, and 60.4%, respectively).

Conclusion: There is a high prevalence of metabolic syndrome among patients with mental disorder admitted to the Mental Hospital of Bali Province. Comprehensive multidisciplinary co-operation is required in the treating those with metabolic syndrome as comorbid.


  1. Wardhani YF, Paramita A. Pelayanan Kesehatan Mental Dalam Hubungannya Dengan Disabilitas Dan Gaya Hidup Masyarakat Indonesia (Analisis Lanjut Riskesdas 2007 Dan 2013). Buletin Penelitian Sistem Kesehatan 2016; Vol, 19 No, 1: 99–107
  2. Papanastasiou E. Interventions for the metabolic syndrome in schizophrenia: a review. Ther Adv Endocrinol Metab 2012; 3(5) 141–62
  3. Kucerovaa J, Babinska Z, Horska K, Kotolova H. The common pathophysiology underlying the metabolic syndrome, schizophrenia and depression: A review. Biomed Pap Med 2015; 159(2):208-14
  4. Yogaratnam J, Biswas N,Vadivel R, Jacob R. Metabolic Complications of Schizophrenia and Antipsychotic Medications: An Updated Review. East Asian Arch Psychiatry 2013;23:21-8
  5. Seow LSE, Chong SA, Wang P, Shafie S, Ong H, Subramaniam M. Metabolic syndrome and cardiovascular risk among institutionalized patients with schizophrenia receiving long term tertiary care. Comprehensive Psychiatry 2017;74:196–203
  6. Shakeri J, Karimi K, Farnia V, Golshani S, Alikhani M. Prevalence of Metabolic Syndrome in Patients with Schizophrenia Referred to Farabi Hospital, Kermanshah, Iran. Oman Medical Journal 2016; Vol, 31:No, 4:270–75
  7. Lee J , Nurjono M, Wong A, Salim A. Prevalence of Metabolic Syndrome Among Patients with Schizophrenia in Singapore. Ann Acad Med Singapore 2012;41:457-62
  8. Lee JS, Kwon JS, Kim D, Kim SW, Kim JJ, et al. Prevalence of Metabolic Syndrome in Patients with Schizophrenia in Korea: A Multicenter Nationwide Cross-Sectional Study. Psychiatry Investig 2017;14(1):44-50
  9. Said MA , Sulaiman AH, Habi M, Das S,et al. Metabolic syndrome and cardiovascular risk among patients with schizophrenia receiving antipsychotics in Malaysia, Singapore Med J 2012; 53(12): 801–07
  10. Jeon SW. Unresolved Issues for Utilization of Atypical Antipsychotics in Schizophrenia: Antipsychotic Polypharmacy and Metabolic Syndrome. Int, J, Mol, Sci 2017; 18: 2174
  11. Kyung Ko Y. The Prevalence of Metabolic Syndrome in Schizophrenic Patients Using Antipsychotics. Clinical Psychopharmacology and Neuroscience 2013;11(2):80-8
  12. Vancampfort D, et al. Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis. World Psychiatry 2015;14:339–47,
  13. Dwipayana MP, Suastika K, Saraswati IMR, Gotera W, Budhiarta AAG, Sutanegara, et al. Prevalensi Sindroma Metabolik Pada Populasi Penduduk Bali, Indonesia. J Peny Dalam 2011; Volume 12 Nomor 1

How to Cite

Prabawa, I. P. A. G., Witari, P. K., & Ariawan, I. W. Y. (2019). Gambaran sindrom metabolik pada pasien gangguan jiwa yang dirawat di rumah sakit jiwa provinsi Bali. Intisari Sains Medis, 10(2).




Search Panel

I Putu Arya Giri Prabawa
Google Scholar
ISM Journal

Putu Kristalina Witari
Google Scholar
ISM Journal

I Wayan Yuna Ariawan
Google Scholar
ISM Journal