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Herpes zoster disseminated in immunocompromised (ALL) children

  • William Grandinata ,
  • I Wayan Gustawan ,
  • I Made Gede Dwi Lingga Utama ,
  • Prima Sanjiwani Saraswati Sudarsa ,

Abstract

Background: Herpes Zoster is an acute vesicular eruption caused by the reactivation of the latent varicella-zoster virus in the sensory ganglia after exposure to primary varicella infection. The prevalence of shingles is not influenced by race, gender, or season. The incidence of this disease increases with age and is rarely found in children. Shingles can occur in a child with a history of intrauterine primary infection, immunocompromised conditions, and with varicella in the first year of life. Management includes providing information and education about diseases and precipitating factors and explaining the treatment. This case report described the clinical manifestation and the management of herpes zoster in an immunocompromised (Acute Lymphoblastic Leukemia) child.

Case Presentation: A 17-year-old girl complained of clear fluid and redness in the thighs, legs, back and abdomen. Patients complain of pain in such lesions. Itching is also felt, but more of a burning sensation in the lesion. Patients also complain of fever. On physical examination, there appears to be a vesicle-bullae multiple firm boundary efflorescence of a spherical shape measuring 0.3-0.5 cm – 1x 1.5 cm. Some lesions are confluent and are scattered discretely over the erythema bark. The patient has no clear history of varicella vaccine and has never had chickenpox (varicella) before. The patient was also diagnosed with ALL (acute lymphoblastic leukemia) for 10 years and has undergone chemotherapy according to protocol. The Tzank test in this patient was positive. The pediatric tropical infection division treats the patient and is also treated with the dermato-venerology division. These patients have been treated with acyclovir, sodium fusidate, salicylic powder on intact bubbles, and 0.9% Nacl compresses on erosion or bubble bursts.

Conclusion: The management of Herpes zoster in pediatric patients with immunocompromised is still carried out holistically by providing antivirals and appropriate wound care in lesions that arise.

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How to Cite

Grandinata, W., Gustawan, I. W., Utama, I. M. G. D. L. ., & Sudarsa, P. S. S. . (2023). Herpes zoster disseminated in immunocompromised (ALL) children. Intisari Sains Medis, 14(2), 913–917. https://doi.org/10.15562/ism.v14i2.1786

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William Grandinata
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I Wayan Gustawan
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I Made Gede Dwi Lingga Utama
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Prima Sanjiwani Saraswati Sudarsa
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